Fast-SNP: a fast matrix pre-processing algorithm for efficient loopless flux optimization of metabolic models
Motivation: Computation of steady-state flux solutions in large metabolic models is routinely performed using flux balance analysis based on a simple LP (Linear Programming) formulation. A minimal requirement for thermodynamic feasibility of the flux solution is the absence of internal loops, which...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167067/ |