Fast-SNP: a fast matrix pre-processing algorithm for efficient loopless flux optimization of metabolic models

Motivation: Computation of steady-state flux solutions in large metabolic models is routinely performed using flux balance analysis based on a simple LP (Linear Programming) formulation. A minimal requirement for thermodynamic feasibility of the flux solution is the absence of internal loops, which...

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Bibliographic Details
Main Authors: Saa, Pedro A., Nielsen, Lars K.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167067/