NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing
Lytic granule convergence to the MTOC prepares NK cells for cytotoxic effector function. Hsu et al. demonstrate that convergence increases specificity in directed secretion, thereby preventing bystander killing.
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166499/ |