LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining
DNA repair is critical for genome integrity. Lawrence et al. reveal a role for a novel complex that links the nucleus to microtubules to promote accurate repair through both inhibition of error-prone nonhomologous end joining and promotion of homologous recombination.
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
The Rockefeller University Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166498/ |