Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably?
During virus assembly, all retroviruses specifically encapsidate two copies of full-length viral genomic RNA in the form of a non-covalently linked RNA dimer. The absolute conservation of this unique genome structure within the Retroviridae family is strong evidence that a dimerized genome is of cri...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2004
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516451/ |