Investigation of hydrophobic moment and hydrophobicity properties for transmembrane α-helices

Integral membrane proteins are the primary targets of novel drugs but are largely without solved structures. As a consequence, hydrophobic moment plot methodology is often used to identify putative transmembrane α-helices of integral membrane proteins, based on their local maximum mean hydrophobic m...

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Bibliographic Details
Main Authors: Wallace, James, Daman, Onkabetse A, Harris, Frederick, Phoenix, David A
Format: Online
Language:English
Published: BioMed Central 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516255/