Mosquito larvicide BinAB revealed by de novo phasing with an X-ray laser

BinAB is a naturally occurring paracrystalline larvicide distributed worldwide to combat the devastating diseases borne by mosquitoes. These crystals are composed of homologous molecules, BinA and BinB, which play distinct roles in the multi-step intoxication process, transforming from harmless, rob...

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Bibliographic Details
Main Authors: Colletier, Jacques-Philippe, Sawaya, Michael R., Gingery, Mari, Rodriguez, Jose A., Cascio, Duilio, Brewster, Aaron S., Michels-Clark, Tara, Hice, Robert H., Coquelle, Nicolas, Boutet, Sébastien, Williams, Garth J., Messerschmidt, Marc, DePonte, Daniel P., Sierra, Raymond G., Laksmono, Hartawan, Koglin, Jason E., Hunter, Mark S., Park, Hyun-Woo, Uervirojnangkoorn, Monarin, Bideshi, Dennis K., Brunger, Axel T., Federici, Brian A., Sauter, Nicholas K., Eisenberg, David S.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161637/