Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression

Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression

•Shared genetics and couple-associated environment are major contributors to the risk of depression.•The common-variant-associated genetic correlation between MDD and SDD was very high (r = 1.00, se = 0.20).•Lower correlations were detected for pedigree-associated genetics and couple-shared environm...

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Main Authors: Zeng, Yanni, Navarro, Pau, Xia, Charley, Amador, Carmen, Fernandez-Pujals, Ana M., Thomson, Pippa A., Campbell, Archie, Nagy, Reka, Clarke, Toni-Kim, Hafferty, Jonathan D., Smith, Blair H., Hocking, Lynne J., Padmanabhan, Sandosh, Hayward, Caroline, MacIntyre, Donald J., Porteous, David J, Haley, Chris S., McIntosh, Andrew M.
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161419/

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