The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection

The main features of lung infection and inflammation are a massive recruitment of neutrophils and the subsequent release of neutrophil serine proteases (NSPs). Anti-infectious and/or anti-inflammatory treatments must be tested on a suitable animal model. Mice models do not replicate several aspects...

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Bibliographic Details
Main Authors: Chevaleyre, Claire, Riou, Mickaël, Bréa, Déborah, Vandebrouck, Clarisse, Barc, Céline, Pezant, Jérémy, Melo, Sandrine, Olivier, Michel, Delaunay, Rémy, Boulesteix, Olivier, Berthon, Patricia, Rossignol, Christelle, Burlaud Gaillard, Julien, Becq, Frédéric, Gauthier, Francis, Si-Tahar, Mustapha, Meurens, François, Berri, Mustapha, Caballero-Posadas, Ignacio, Attucci, Sylvie
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161375/