Chromoendoscopy in combination with random biopsies does not improve detection of gastric cancer foci in CDH1 mutation positive patients

Background and study aims: Hereditary diffuse gastric cancer (HGGC), an autosomal dominant tumor-syndrome, accounts for 1 % to 3 % of gastric cancers worldwide. Presumably 30 % to 40 % of all patients fulfilling the clinical guidelines for HDGC are carriers of a pathogenic mutation in the CDH1 gene...

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Main Authors: Hüneburg, Robert, Marwitz, Tim, van Heteren, Peer, Weismüller, Tobias J., Trebicka, Jonel, Adam, Ronja, Aretz, Stefan, Perez Bouza, Alberto, Pantelis, Dimitrios, Kalff, Jörg C., Nattermann, Jacob, Strassburg, Cristian P.
Format: Online
Language:English
Published: © Georg Thieme Verlag KG 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161122/