Chromoendoscopy in combination with random biopsies does not improve detection of gastric cancer foci in CDH1 mutation positive patients
Background and study aims: Hereditary diffuse gastric cancer (HGGC), an autosomal dominant tumor-syndrome, accounts for 1 % to 3 % of gastric cancers worldwide. Presumably 30 % to 40 % of all patients fulfilling the clinical guidelines for HDGC are carriers of a pathogenic mutation in the CDH1 gene...
Main Authors: | , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
© Georg Thieme Verlag KG
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161122/ |