Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis

Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis

Pancreatic stellate cells (PSCs) play a major role to fibrotic islet destruction observed in diabetic patients and animal model of diabetes. Exendin-4 (Ex-4) is a potent insulinotropic agent and has been approved for the treatment of type 2 diabetes. However, there have been no reports demonstrating...

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Bibliographic Details
Main Authors: Kim, Ji-Won, Park, Shin-Young, You, Young-Hye, Ham, Dong-Sik, Lee, Seung-Hwan, Yang, Hae Kyung, Jeong, In-Kyung, Ko, Seung-Hyun, Yoon, Kun-Ho
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157943/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157943/

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