Dysregulation of Ubiquitin-Proteasome System in Neurodegenerative Diseases

The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways, where abnormal UPS function has been observed in cancer and neurological diseases. Many neurodegenerative diseases share a common pathological feature, namely intracellular ubiquitin-positive inclusions formed by...

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Bibliographic Details
Main Authors: Zheng, Qiuyang, Huang, Timothy, Zhang, Lishan, Zhou, Ying, Luo, Hong, Xu, Huaxi, Wang, Xin
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156861/