Diarrheagenic Escherichia coli

Diarrheagenic Escherichia coli

Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe public healt...

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Main Authors: Gomes, Tânia A.T., Elias, Waldir P., Scaletsky, Isabel C.A., Guth, Beatriz E.C., Rodrigues, Juliana F., Piazza, Roxane M.F., Ferreira, Luís C.S., Martinez, Marina B.
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156508/
id pubmed-5156508
recordtype oai_dc
spelling pubmed-51565082016-12-19 Diarrheagenic Escherichia coli Gomes, Tânia A.T. Elias, Waldir P. Scaletsky, Isabel C.A. Guth, Beatriz E.C. Rodrigues, Juliana F. Piazza, Roxane M.F. Ferreira, Luís C.S. Martinez, Marina B. Review Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe public health problem and a major cause of morbidity and mortality in infants and young children, especially in developing countries. E. coli strains that cause diarrhea have evolved by acquiring, through horizontal gene transfer, a particular set of characteristics that have successfully persisted in the host. According to the group of virulence determinants acquired, specific combinations were formed determining the currently known E. coli pathotypes, which are collectively known as diarrheagenic E. coli. In this review, we have gathered information on current definitions, serotypes, lineages, virulence mechanisms, epidemiology, and diagnosis of the major diarrheagenic E. coli pathotypes. Elsevier 2016-11-05 /pmc/articles/PMC5156508/ /pubmed/27866935 http://dx.doi.org/10.1016/j.bjm.2016.10.015 Text en © 2016 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Gomes, Tânia A.T.
Elias, Waldir P.
Scaletsky, Isabel C.A.
Guth, Beatriz E.C.
Rodrigues, Juliana F.
Piazza, Roxane M.F.
Ferreira, Luís C.S.
Martinez, Marina B.
spellingShingle Gomes, Tânia A.T.
Elias, Waldir P.
Scaletsky, Isabel C.A.
Guth, Beatriz E.C.
Rodrigues, Juliana F.
Piazza, Roxane M.F.
Ferreira, Luís C.S.
Martinez, Marina B.
Diarrheagenic Escherichia coli
author_facet Gomes, Tânia A.T.
Elias, Waldir P.
Scaletsky, Isabel C.A.
Guth, Beatriz E.C.
Rodrigues, Juliana F.
Piazza, Roxane M.F.
Ferreira, Luís C.S.
Martinez, Marina B.
author_sort Gomes, Tânia A.T.
title Diarrheagenic Escherichia coli
title_short Diarrheagenic Escherichia coli
title_full Diarrheagenic Escherichia coli
title_fullStr Diarrheagenic Escherichia coli
title_full_unstemmed Diarrheagenic Escherichia coli
title_sort diarrheagenic escherichia coli
description Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe public health problem and a major cause of morbidity and mortality in infants and young children, especially in developing countries. E. coli strains that cause diarrhea have evolved by acquiring, through horizontal gene transfer, a particular set of characteristics that have successfully persisted in the host. According to the group of virulence determinants acquired, specific combinations were formed determining the currently known E. coli pathotypes, which are collectively known as diarrheagenic E. coli. In this review, we have gathered information on current definitions, serotypes, lineages, virulence mechanisms, epidemiology, and diagnosis of the major diarrheagenic E. coli pathotypes.
publisher Elsevier
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156508/
_version_ 1613780977791795200

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