The latent cytomegalovirus decreases telomere length by microcompetition
Reduced telomere length has been associated with aging and age-related diseases. Latent infection with the Cytomegalovirus (CMV) induces telomere shortening in the infected cells. Latent CMV infection may cause reduced telomere length via GABP transcription factor deficiency, according to the Microc...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
De Gruyter Open
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152988/ |
| Summary: | Reduced telomere length has been associated with aging and age-related diseases. Latent infection with the Cytomegalovirus (CMV) induces telomere shortening in the infected cells. Latent CMV infection may cause reduced telomere length via GABP transcription factor deficiency, according to the Microcompetition Theory. Microcompetition and viral-induced transcription factor deficiency is important since most people harbor a latent viral infection. |
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