Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p′-dde levels in a population-based sample

Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p′-dde levels in a population-based sample

•A whole genome scan was used to investigate the metabolic route of p,p′-DDE in human.•Genetic variation in the CYP2B6 gene was associated with p,p′-DDE levels.•Methylation close to the same gene was associated with p,p′-DDE levels.•Modern genetic analyses showed CYP2B6 to be linked to p,p′-DDE leve...

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Bibliographic Details
Main Authors: Lind, Lars, Ng, Esther, Ingelsson, Erik, Lindgren, Cecilia, Salihovic, Samira, van Bavel, Bert, Mahajan, Anubha, Lampa, Erik, Morris, Andrew P., Lind, P. Monica
Format: Online
Language:English
Published: Elsevier Science 2017
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152752/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5152752/

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