HPLC estimation of iothalamate to measure glomerular filtration rate in humans

Glomerular filtration rate (GFR) is usually determined by estimation of iothalamate (IOT) clearance. We have developed and validated an accurate and robust method for the analysis of IOT in human plasma and urine. The mobile phase consisted of methanol and 50 mM sodium phosphate (10:90; v/v). Flow r...

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Bibliographic Details
Main Authors: Shah, Iltaf, Barker, James, Naughton, Declan P., Barton, Stephen J., Ashraf, Syed Salman
Format: Online
Language:English
Published: Springer International Publishing 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151096/