Very Late Antigen-1 Marks Functional Tumor-Resident CD8 T Cells and Correlates with Survival of Melanoma Patients

A major limiting factor in the success of immunotherapy is tumor infiltration by CD8+ T cells, a process that remains poorly understood. In the present study, we characterized homing receptors expressed by human melanoma-specific CD8+ T cells. Our data reveal that P-selectin binding and expression o...

Full description

Bibliographic Details
Main Authors: Murray, Timothy, Fuertes Marraco, Silvia A., Baumgaertner, Petra, Bordry, Natacha, Cagnon, Laurène, Donda, Alena, Romero, Pedro, Verdeil, Grégory, Speiser, Daniel E.
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150229/