ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages

Adenosine triphosphate (ATP) is released by bacteria and host cells during bacterial infection as well as sterile tissue injury, acting as an inducer of inflammasome activation. Previous studies have shown that ATP treatment leads to AMP-activated protein kinase (AMPK) activation. However, it is unc...

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Bibliographic Details
Main Authors: Zha, Qing-Bing, Wei, Hong-Xia, Li, Chen-Guang, Liang, Yi-Dan, Xu, Li-Hui, Bai, Wen-Jing, Pan, Hao, He, Xian-Hui, Ouyang, Dong-Yun
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149551/