Molecular Evolution of PTEN Pseudogenes in Mammals

Phosphatase and tensin homolog (PTEN) is a tumor-suppressor gene. PTEN pseudogene (PTENp) acts as an endogenous RNA, which regulates its parental gene by competitively binding to the 3’ UTR of PTEN gene in the human. Despite the importance of this pseudogene, little is known about the molecular evol...

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Bibliographic Details
Main Authors: Tang, Jingsi, Ning, Ruihong, Zeng, Bo, Li, Ying
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148010/