The rs3957357C>T SNP in GSTA1 Is Associated with a Higher Risk of Occurrence of Hepatocellular Carcinoma in European Individuals

Glutathione S-transferases (GSTs) detoxify toxic molecules by conjugation with reduced glutathione and regulate cell signaling. Single nucleotide polymorphisms (SNPs) of GST genes have been suggested to affect GST functions and thus to increase the risk of human hepatocellular carcinoma (HCC). As GS...

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Bibliographic Details
Main Authors: Akhdar, Hanane, El Shamieh, Said, Musso, Orlando, Désert, Romain, Joumaa, Wissam, Guyader, Dominique, Aninat, Caroline, Corlu, Anne, Morel, Fabrice
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147914/