Bypass of Candida albicans Filamentation/Biofilm Regulators through Diminished Expression of Protein Kinase Cak1

Biofilm formation on implanted medical devices is a major source of lethal invasive infection by Candida albicans. Filamentous growth of this fungus is tied to biofilm formation because many filamentation-associated genes are required for surface adherence. Cell cycle or cell growth defects can indu...

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Bibliographic Details
Main Authors: Woolford, Carol A., Lagree, Katherine, Xu, Wenjie, Aleynikov, Tatyana, Adhikari, Hema, Sanchez, Hiram, Cullen, Paul J., Lanni, Frederick, Andes, David R., Mitchell, Aaron P.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147786/