Progesterone Alters Kynurenine Pathway Activation in IFN-γ-Activated Macrophages – Relevance for Neuroinflammatory Diseases

We have previously demonstrated that the kynurenine pathway (KP), the major biochemical pathway for tryptophan metabolism, is dysregulated in many inflammatory disorders that are often associated with sexual dimorphisms. We aimed to identify a potential functional interaction between the KP and gona...

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Bibliographic Details
Main Authors: de Bie, J., Lim, C. K., Guillemin, G. J.
Format: Online
Language:English
Published: Libertas Academica 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147515/