Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis

Background: Persons with Multiple Sclerosis frequently have gait deficits that lead to diminished activities of daily living. Identification of motoneuron activity patterns may elucidate new insight into impaired locomotor coordination and underlying neural systems. The aim of the present study was...

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Main Authors:	Lencioni, Tiziana, Jonsdottir, Johanna, Cattaneo, Davide, Crippa, Alessandro, Gervasoni, Elisa, Rovaris, Marco, Bizzi, Emilio, Ferrarin, Maurizio
Format:	Online
Language:	English
Published:	Frontiers Media S.A. 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145858/

id	pubmed-5145858
recordtype	oai_dc
spelling	pubmed-51458582016-12-23 Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis Lencioni, Tiziana Jonsdottir, Johanna Cattaneo, Davide Crippa, Alessandro Gervasoni, Elisa Rovaris, Marco Bizzi, Emilio Ferrarin, Maurizio Neuroscience Background: Persons with Multiple Sclerosis frequently have gait deficits that lead to diminished activities of daily living. Identification of motoneuron activity patterns may elucidate new insight into impaired locomotor coordination and underlying neural systems. The aim of the present study was to investigate muscle synergies, identified by motor modules and their activation profiles, in persons with Multiple Sclerosis (PwMS) during walking compared to those of healthy subjects (HS), as well as, exploring relationship of muscle synergies with walking ability of PwMS. Frontiers Media S.A. 2016-12-09 /pmc/articles/PMC5145858/ /pubmed/28018193 http://dx.doi.org/10.3389/fnhum.2016.00620 Text en Copyright © 2016 Lencioni, Jonsdottir, Cattaneo, Crippa, Gervasoni, Rovaris, Bizzi and Ferrarin. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Lencioni, Tiziana Jonsdottir, Johanna Cattaneo, Davide Crippa, Alessandro Gervasoni, Elisa Rovaris, Marco Bizzi, Emilio Ferrarin, Maurizio
spellingShingle	Lencioni, Tiziana Jonsdottir, Johanna Cattaneo, Davide Crippa, Alessandro Gervasoni, Elisa Rovaris, Marco Bizzi, Emilio Ferrarin, Maurizio Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis
author_facet	Lencioni, Tiziana Jonsdottir, Johanna Cattaneo, Davide Crippa, Alessandro Gervasoni, Elisa Rovaris, Marco Bizzi, Emilio Ferrarin, Maurizio
author_sort	Lencioni, Tiziana
title	Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis
title_short	Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis
title_full	Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis
title_fullStr	Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis
title_full_unstemmed	Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis
title_sort	are modular activations altered in lower limb muscles of persons with multiple sclerosis during walking? evidence from muscle synergies and biomechanical analysis
description	Background: Persons with Multiple Sclerosis frequently have gait deficits that lead to diminished activities of daily living. Identification of motoneuron activity patterns may elucidate new insight into impaired locomotor coordination and underlying neural systems. The aim of the present study was to investigate muscle synergies, identified by motor modules and their activation profiles, in persons with Multiple Sclerosis (PwMS) during walking compared to those of healthy subjects (HS), as well as, exploring relationship of muscle synergies with walking ability of PwMS.
publisher	Frontiers Media S.A.
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145858/
_version_	1613767493069832192

Are Modular Activations Altered in Lower Limb Muscles of Persons with Multiple Sclerosis during Walking? Evidence from Muscle Synergies and Biomechanical Analysis

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