Development of PET Imaging to Visualize Activated Macrophages Accumulated in the Transplanted iPSc-Derived Cardiac Myocytes of Allogeneic Origin for Detecting the Immune Rejection of Allogeneic Cell Transplants in Mice

Development of PET Imaging to Visualize Activated Macrophages Accumulated in the Transplanted iPSc-Derived Cardiac Myocytes of Allogeneic Origin for Detecting the Immune Rejection of Allogeneic Cell Transplants in Mice

Allogeneic transplantation (Tx) of induced pluripotent stem cells (iPSCs) is a promising tissue regeneration therapy. However, this inevitably induces macrophage-mediated immune response against the graft, limiting its therapeutic efficacy. Monitoring the magnitude of the immune response using imagi...

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Bibliographic Details
Main Authors: Kashiyama, Noriyuki, Miyagawa, Shigeru, Fukushima, Satsuki, Kawamura, Takuji, Kawamura, Ai, Yoshida, Shohei, Harada, Akima, Watabe, Tadashi, Kanai, Yasukazu, Toda, Koichi, Hatazawa, Jun, Sawa, Yoshiki
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145152/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145152/

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