Temporary Depletion of Microglia during the Early Postnatal Period Induces Lasting Sex-Dependent and Sex-Independent Effects on Behavior in Rats

Microglia are the primary immune cells of the brain and function in multiple ways to facilitate proper brain development. However, our current understanding of how these cells influence the later expression of normal behaviors is lacking. Using the laboratory rat, we administered liposomal clodronat...

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Bibliographic Details
Main Authors: VanRyzin, Jonathan W., Yu, Stacey J., Perez-Pouchoulen, Miguel, McCarthy, Margaret M.
Format: Online
Language:English
Published: Society for Neuroscience 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144556/