TMEM2 inhibits hepatitis B virus infection in HepG2 and HepG2.2.15 cells by activating the JAK–STAT signaling pathway

We have previously observed the downregulation of TMEM2 in the liver tissue of patients with chronic hepatitis B virus (HBV) infection and in HepG2.2.15 cells with HBV genomic DNA. In the present study, we investigated the role and mechanism of TMEM2 in HepG2 and HepG2.2.15 during HBV infection HepG...

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Bibliographic Details
Main Authors: Zhu, X, Xie, C, Li, Y-m, Huang, Z-l, Zhao, Q-y, Hu, Z-x, Wang, P-p, Gu, Y-r, Gao, Z-l, Peng, L
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143376/