Progress and challenges in bioinformatics approaches for enhancer identification

Enhancers are cis-acting DNA elements that play critical roles in distal regulation of gene expression. Identifying enhancers is an important step for understanding distinct gene expression programs that may reflect normal and pathogenic cellular conditions. Experimental identification of enhancers...

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Bibliographic Details
Main Authors: Kleftogiannis, Dimitrios, Kalnis, Panos, Bajic, Vladimir B.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142011/