A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion

The conserved SecYEG protein-conducting channel and the accessory proteins SecDF-YajC and YidC constitute the bacterial holo-translocon (HTL), capable of protein-secretion and membrane-protein insertion. By employing an integrative approach combining small-angle neutron scattering (SANS), low-resolu...

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Bibliographic Details
Main Authors: Botte, Mathieu, Zaccai, Nathan R., Nijeholt, Jelger Lycklama à., Martin, Remy, Knoops, Kèvin, Papai, Gabor, Zou, Juan, Deniaud, Aurélien, Karuppasamy, Manikandan, Jiang, Qiyang, Roy, Abhishek Singha, Schulten, Klaus, Schultz, Patrick, Rappsilber, Juri, Zaccai, Giuseppe, Berger, Imre, Collinson, Ian, Schaffitzel, Christiane
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141469/