Development of novel noninvasive prenatal testing protocol for whole autosomal recessive disease using picodroplet digital PCR

Development of novel noninvasive prenatal testing protocol for whole autosomal recessive disease using picodroplet digital PCR

We developed a protocol of noninvasive prenatal testing (NIPT), employing a higher-resolution picodroplet digital PCR, to detect genetic imbalance in maternal plasma DNA (mpDNA) caused by cell-free fetal DNA (cffDNA). In the present study, this approach was applied to four families with autosomal re...

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Bibliographic Details
Main Authors: Chang, Mun Young, Kim, Ah Reum, Kim, Min Young, Kim, Soyoung, Yoon, Jinsun, Han, Jae Joon, Ahn, Soyeon, Kang, Changsoo, Choi, Byung Yoon
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141438/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141438/

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