SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy

Trehalose is a disaccharide demonstrated to mitigate disease burden in multiple murine neurodegenerative models. We recently revealed that trehalose rapidly induces hepatic autophagy and abrogates hepatic steatosis by inhibiting hexose transport via the SLC2A family of facilitative transporters. Pri...

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Bibliographic Details
Main Authors: Mayer, Allyson L., Higgins, Cassandra B., Heitmeier, Monique R., Kraft, Thomas E., Qian, Xia, Crowley, Jan R., Hyrc, Krzysztof L., Beatty, Wandy L., Yarasheski, Kevin E., Hruz, Paul W., DeBosch, Brian J.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138640/

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