Low-Dose Lithium Stabilizes Human Endothelial Barrier by Decreasing MLC Phosphorylation and Universally Augments Cholinergic Vasorelaxation Capacity in a Direct Manner

Low-Dose Lithium Stabilizes Human Endothelial Barrier by Decreasing MLC Phosphorylation and Universally Augments Cholinergic Vasorelaxation Capacity in a Direct Manner

Lithium at serum concentrations up to 1 mmol/L has been used in patients suffering from bipolar disorder for decades and has recently been shown to reduce the risk for ischemic stroke in these patients. The risk for stroke and thromboembolism depend not only on cerebral but also on general endotheli...

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Bibliographic Details
Main Authors: Bosche, Bert, Molcanyi, Marek, Rej, Soham, Doeppner, Thorsten R., Obermann, Mark, Müller, Daniel J., Das, Anupam, Hescheler, Jürgen, Macdonald, R. Loch, Noll, Thomas, Härtel, Frauke V.
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138228/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138228/

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