Cellular stress responses in protein misfolding diseases

Many human diseases, particularly neurodegenerative diseases, are associated with protein misfolding. Cellular protein quality control includes all processes that ensure proper protein folding and thus prevent the toxic consequences of protein misfolding. The heat shock response (HSR) and the unfold...

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Bibliographic Details
Main Author: Duennwald, Martin L
Format: Online
Language:English
Published: Future Science Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137871/