The ace-1 Locus Is Amplified in All Resistant Anopheles gambiae Mosquitoes: Fitness Consequences of Homogeneous and Heterogeneous Duplications

Gene copy-number variations are widespread in natural populations, but investigating their phenotypic consequences requires contemporary duplications under selection. Such duplications have been found at the ace-1 locus (encoding the organophosphate and carbamate insecticides’ target) in the mosquit...

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Main Authors: Assogba, Benoît S., Milesi, Pascal, Djogbénou, Luc S., Berthomieu, Arnaud, Makoundou, Patrick, Baba-Moussa, Lamine S., Fiston-Lavier, Anna-Sophie, Belkhir, Khalid, Labbé, Pierrick, Weill, Mylène
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137868/