Diabetes negatively affects cortical and striatal GABAergic neurons: an effect that is partially counteracted by exendin-4

Diabetes negatively affects specific subtypes of inhibitory neurons in brain areas that regulate sensory and motor functions. This impairment can be partially reversed by exendin-4 (Ex-4). The findings could contribute to the development of treatments against diabetic neurological complications.

Bibliographic Details
Main Authors: Larsson, Martin, Lietzau, Grazyna, Nathanson, David, Östenson, Claes-Göran, Mallard, Carina, Johansson, Maria E., Nyström, Thomas, Patrone, Cesare, Darsalia, Vladimer
Format: Online
Language:English
Published: Portland Press Ltd. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137538/