Insightful directed evolution of Escherichia coli quorum sensing promoter region of the lsrACDBFG operon: a tool for synthetic biology systems and protein expression

Quorum sensing (QS) regulates many natural phenotypes (e.q. virulence, biofilm formation, antibiotic resistance), and its components, when incorporated into synthetic genetic circuits, enable user-directed phenotypes. We created a library of Escherichia coli lsr operon promoters using error-prone PC...

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Bibliographic Details
Main Authors: Hauk, Pricila, Stephens, Kristina, Mckay, Ryan, Virgile, Chelsea Ryan, Ueda, Hana, Ostermeier, Marc, Ryu, Kyoung-Seok, Sintim, Herman O., Bentley, William E.
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137460/