All‐trans retinoic acid (ATRA) in non‐promyelocytic acute myeloid leukemia (AML): results of combination of ATRA with low‐dose Ara‐C in three elderly patients with NPM1‐mutated AML unfit for intensive chemotherapy and review of the literature

All‐trans retinoic acid (ATRA) in non‐promyelocytic acute myeloid leukemia (AML): results of combination of ATRA with low‐dose Ara‐C in three elderly patients with NPM1‐mutated AML unfit for intensive chemotherapy and review of the literature

Based upon the clinical behavior of three patients, we suggest that the combination of low‐dose Ara‐C and all‐trans retinoic acid may potentially be effective in some elderly patients, unfit for intensive chemotherapy, affected with NPM1‐mutated acute myeloid leukemia without FLT3 mutations, warrant...

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Bibliographic Details
Main Authors: Forghieri, Fabio, Bigliardi, Sara, Quadrelli, Chiara, Morselli, Monica, Potenza, Leonardo, Paolini, Ambra, Colaci, Elisabetta, Barozzi, Patrizia, Zucchini, Patrizia, Riva, Giovanni, Vallerini, Daniela, Lagreca, Ivana, Marasca, Roberto, Narni, Franco, Venditti, Adriano, Martelli, Maria Paola, Falini, Brunangelo, Lo Coco, Francesco, Amadori, Sergio, Luppi, Mario
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134148/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134148/

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