IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells

IBTK Differently Modulates Gene Expression and RNA Splicing in HeLa and K562 Cells

The IBTK gene encodes the major protein isoform IBTKα that was recently characterized as substrate receptor of Cul3-dependent E3 ligase, regulating ubiquitination coupled to proteasomal degradation of Pdcd4, an inhibitor of translation. Due to the presence of Ankyrin-BTB-RCC1 domains that mediate se...

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Bibliographic Details
Main Authors: Fiume, Giuseppe, Scialdone, Annarita, Rizzo, Francesca, De Filippo, Maria Rosaria, Laudanna, Carmelo, Albano, Francesco, Golino, Gaetanina, Vecchio, Eleonora, Pontoriero, Marilena, Mimmi, Selena, Ceglia, Simona, Pisano, Antonio, Iaccino, Enrico, Palmieri, Camillo, Paduano, Sergio, Viglietto, Giuseppe, Weisz, Alessandro, Scala, Giuseppe, Quinto, Ileana
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133848/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133848/

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