NOX isoforms in the development of abdominal aortic aneurysm

Oxidative stress plays an important role in the formation of abdominal aortic aneurysm (AAA), and we have recently established a causal role of uncoupled eNOS in this severe human disease. We have also shown that activation of NADPH oxidase (NOX) lies upstream of uncoupled eNOS. Therefore, identific...

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Bibliographic Details
Main Authors: Siu, Kin Lung, Li, Qiang, Zhang, Yixuan, Guo, Jun, Youn, Ji Youn, Du, Jie, Cai, Hua
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133668/