Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity

Regulation of gene expression in immune cells is known to be under genetic control, and likely contributes to susceptibility to autoimmune diseases, such as multiple sclerosis (MS). How this occurs in concert across multiple immune cell types is poorly understood. Using a mouse model that harnesses...

Full description

Bibliographic Details
Main Authors: Bearoff, Frank, del Rio, Roxana, Case, Laure K., Dragon, Julie A., Nguyen-Vu, Trang, Lin, Chin-Yo, Blankenhorn, Elizabeth P., Teuscher, Cory, Krementsov, Dimitry N.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133152/