Anti-Hu antibodies activate enteric and sensory neurons

IgG of type 1 anti-neuronal nuclear antibody (ANNA-1, anti-Hu) specificity is a serological marker of paraneoplastic neurological autoimmunity (including enteric/autonomic) usually related to small-cell lung carcinoma. We show here that IgG isolated from such sera and also affinity-purified anti-HuD...

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Bibliographic Details
Main Authors: Li, Qin, Michel, Klaus, Annahazi, Anita, Demir, Ihsan E., Ceyhan, Güralp O., Zeller, Florian, Komorowski, Lars, Stöcker, Winfried, Beyak, Michael J., Grundy, David, Farrugia, Gianrico, De Giorgio, Roberto, Schemann, Michael
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131267/