Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation

Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation

The process of intravasation involving transendothelial migration is a key step in metastatic spread. How the triple cell complex composed of a macrophage, Mena over-expressing tumor cell and endothelial cell, called the tumor microenvironment of metastasis (TMEM), facilitates tumor cell transendoth...

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Bibliographic Details
Main Authors: Pignatelli, Jeanine, Bravo-Cordero, Jose Javier, Roh-Johnson, Minna, Gandhi, Saumil J., Wang, Yarong, Chen, Xiaoming, Eddy, Robert J., Xue, Alice, Singer, Robert H., Hodgson, Louis, Oktay, Maja H., Condeelis, John S.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129016/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129016/

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