Obesity- and gender-dependent role of endogenous somatostatin and cortistatin in the regulation of endocrine and metabolic homeostasis in mice

Somatostatin (SST) and cortistatin (CORT) regulate numerous endocrine secretions and their absence [knockout (KO)-models] causes important endocrine-metabolic alterations, including pituitary dysregulations. We have demonstrated that the metabolic phenotype of single or combined SST/CORT KO-models i...

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Bibliographic Details
Main Authors: Luque, Raúl M., Cordoba-Chacon, José, Pozo-Salas, Ana I., Porteiro, Begoña, de Lecea, Luis, Nogueiras, Rubén, Gahete, Manuel D., Castaño, Justo P.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128804/