Interaction of PPARα With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis
Peroxisome proliferator–activated receptor-α (PPARα) displays renoprotective effects with an unclear mechanism. Aberrant activation of the canonical Wnt pathway plays a key role in renal fibrosis. Renal levels of PPARα were downregulated in both type 1 and type 2 diabetes models. The PPARα agonist f...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
American Diabetes Association
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127249/ |