N-methyl-2-pyridone-5-carboxamide (2PY)—Major Metabolite of Nicotinamide: An Update on an Old Uremic Toxin

N-methyl-2-pyridone-5-carboxamide (2PY)—Major Metabolite of Nicotinamide: An Update on an Old Uremic Toxin

N-methyl-2-pyridone-5-carboxamide (2PY, a major metabolite of nicotinamide, NAM) was recently identified as a uremic toxin. Recent interventional trials using NAM to treat high levels of phosphorus in end-stage renal disease have highlighted new potential uremic toxicities of 2PY. In the context of...

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Bibliographic Details
Main Authors: Lenglet, Aurélie, Liabeuf, Sophie, Bodeau, Sandra, Louvet, Loïc, Mary, Aurélien, Boullier, Agnès, Lemaire-Hurtel, Anne Sophie, Jonet, Alexia, Sonnet, Pascal, Kamel, Said, Massy, Ziad A.
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127135/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127135/

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