Interactions between the HIV-1 Unspliced mRNA and Host mRNA Decay Machineries
The human immunodeficiency virus type-1 (HIV-1) unspliced transcript is used both as mRNA for the synthesis of structural proteins and as the packaged genome. Given the presence of retained introns and instability AU-rich sequences, this viral transcript is normally retained and degraded in the nucl...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127034/ |