Interactions between the HIV-1 Unspliced mRNA and Host mRNA Decay Machineries

The human immunodeficiency virus type-1 (HIV-1) unspliced transcript is used both as mRNA for the synthesis of structural proteins and as the packaged genome. Given the presence of retained introns and instability AU-rich sequences, this viral transcript is normally retained and degraded in the nucl...

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Bibliographic Details
Main Authors: Toro-Ascuy, Daniela, Rojas-Araya, Bárbara, Valiente-Echeverría, Fernando, Soto-Rifo, Ricardo
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127034/