CD4+ T Cell Fate in Glomerulonephritis: A Tale of Th1, Th17, and Novel Treg Subtypes
Multiple studies have identified CD4+ T cells as central players of glomerulonephritis (GN). Cells of the Th1 and Th17 responses cause renal tissue damage, while Tregs mediate protection. Recently, a high degree of plasticity among these T cell lineages was proposed. During inflammation, Th17 cells...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126430/ |