Characterization of the Canine MHC Class I DLA-88*50101 Peptide Binding Motif as a Prerequisite for Canine T Cell Immunotherapy

Characterization of the Canine MHC Class I DLA-88*50101 Peptide Binding Motif as a Prerequisite for Canine T Cell Immunotherapy

There are limitations in pre-clinical settings using mice as a basis for clinical development in humans. In cancer, similarities exist between humans and dogs; thus, the dog patient can be a link in the transition from laboratory research on mouse models to clinical trials in humans. Knowledge of th...

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Main Authors: Barth, Sharon M., Schreitmüller, Christian M., Proehl, Franziska, Oehl, Kathrin, Lumpp, Leonie M., Kowalewski, Daniel J., Di Marco, Moreno, Sturm, Theo, Backert, Linus, Schuster, Heiko, Stevanović, Stefan, Rammensee, Hans-Georg, Planz, Oliver
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125661/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125661/

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