RU486 Mitigates Hippocampal Pathology Following Status Epilepticus
Status epilepticus (SE) induces rapid hyper-activation of the hypothalamo–pituitary–adrenocortical (HPA) axis. HPA axis hyperactivity results in excess exposure to high levels of circulating glucocorticoids, which are associated with neurotoxicity and depression-like behavior. These observations hav...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124765/ |