RU486 Mitigates Hippocampal Pathology Following Status Epilepticus

Status epilepticus (SE) induces rapid hyper-activation of the hypothalamo–pituitary–adrenocortical (HPA) axis. HPA axis hyperactivity results in excess exposure to high levels of circulating glucocorticoids, which are associated with neurotoxicity and depression-like behavior. These observations hav...

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Bibliographic Details
Main Authors: Wulsin, Aynara C., Herman, James P., Danzer, Steve C.
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124765/