NADP-Dependent Aldehyde Dehydrogenase from Archaeon Pyrobaculum sp.1860: Structural and Functional Features

We present the functional and structural characterization of the first archaeal thermostable NADP-dependent aldehyde dehydrogenase AlDHPyr1147. In vitro, AlDHPyr1147 catalyzes the irreversible oxidation of short aliphatic aldehydes at 60–85°С, and the affinity of AlDHPyr1147 to the NADP+ at 60°С is...

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Bibliographic Details
Main Authors: Bezsudnova, Ekaterina Yu., Petrova, Tatiana E., Artemova, Natalia V., Boyko, Konstantin M., Shabalin, Ivan G., Rakitina, Tatiana V., Polyakov, Konstantin M., Popov, Vladimir O.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121451/