Functional Interaction of Histone Deacetylase 5 (HDAC5) and Lysine-specific Demethylase 1 (LSD1) Promotes Breast Cancer Progression

We have previously demonstrated that crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases (HDACs) facilitates breast cancer proliferation. However, the underlying mechanisms are largely unknown. Here we report that expression of HDAC5 and LSD1 proteins were positively corr...

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Bibliographic Details
Main Authors: Cao, Chunyu, Vasilatos, Shauna N., Bhargava, Rohit, Fine, Jeffrey L., Oesterreich, Steffi, Davidson, Nancy E., Huang, Yi
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121103/