Detection of Endotoxin Contamination of Graphene Based Materials Using the TNF-α Expression Test and Guidelines for Endotoxin-Free Graphene Oxide Production

Nanomaterials may be contaminated with bacterial endotoxin during production and handling, which may confound toxicological testing of these materials, not least when assessing for immunotoxicity. In the present study, we evaluated the conventional Limulus amebocyte lysate (LAL) assay for endotoxin...

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Bibliographic Details
Main Authors: Mukherjee, Sourav P., Lozano, Neus, Kucki, Melanie, Del Rio-Castillo, Antonio E., Newman, Leon, Vázquez, Ester, Kostarelos, Kostas, Wick, Peter, Fadeel, Bengt
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120825/